Ellipse Vascular Treatments: The Clinical Proof

Ellipse Intense Pulsed Light Treatments

A quick definition:
Vascular treatments are treatments of blood vessels, and use of laser and intense pulsed light tends to be restricted to veins, venules (smaller vessels that link veins to capillaries) and capillaries (the smallest blood vessels). The location, structure and rapid flow of blood in arteries and the smaller arterioles makes them unsuitable for light based treatment. Ellipse has two different Intense Pulsed Light applicators, the PR+ (with a waveband from 530-750nm and the VL+ 555-950nm, which allows treatments of vessels at different depths in the skin, as well as an Nd:YAG laser (1064nm). Choosing the correct tool enables Ellipse users to treat vessels of many different sizes, and therefore treatment of many different vascular problems. As always, it is easy to claim success, but Ellipse has a considerable amount of proof – enough to be considered the new gold standard for vascular treatments.

The clinical proof:
Intense pulsed light source for the treatment of facial telangiectasias. P. Bjerring et al. (J Cosmetic & Laser Ther 2001; 3: 169 – 173)

The first Ellipse vascular paper, and one which showed excellent clinical results (All patients showed some improvement, 83% showed a 50% or greater improvement and 67% showed a 75% or greater improvement). Not only that the study showed that the risk of side effects of treatment was lower than with laser, and that no skin cooling was required.

Before and After 4 treatments

Before and After 4 treatments

 Intense pulsed light source for the treatment of dye laser resistant port-wine stains. P. Bjerring et al. (J Cosmetic & Laser Ther 2003; 5: 7-13)

As a quick background information, no treatment has 100% success rates. This study looked at treatment of patients who had previously not responded to the other “state of the art” treatment – Pulsed Dye Laser –  and found that many (all those treated outside a certain central area of the face), called the V2 area) responded to Ellipse Intense Pulsed Light.

Before and After 4 X IPL treatments

Before and After 4 X IPL treatments


The study took a group of German patients and treated part of the PWS with a reputable pulsed dye laser, and part with Ellipse Intense Pulsed Light. Results showed 85% of the treated PWS responded with clearing. Better clearing by PDL was seen in 13%, whereas IPL was superior in 42%. No differences in clearing were recorded in 31%, and concluded ” These preliminary data suggest the IPL technology as a superior treatment option for PWS”.

The superiority of Ellipse Intense Pulsed Light over Pulsed Dye laser was confirmed in a larger study “Comparison of intense pulsed light (IPL) and pulsed dye laser (PDL) in port-wine stain treatment. Michael Drosner et al. (Medical Laser Application 23 (2008) 133 – 140)” and separately by “Split-face comparison of intense pulsed light with short- and long-pulsed dye lasers for the treatment of port-wine stains. Philipp Babilas et al. (Lasers in Surgery and Medicine 42: 720- 727, 2010)

Early treatment of haemangioma in childhood using IPL. M. Drosner (EADV, 16-24 May, 2007)

An important study that found good results in treatment of newborn children with haemangiomas. However, this has partly been overtaken by use of the drug propranolol.

Progressive disseminated essential telangiectasia and erythrosis interfollicularis colli as examples for successful treatment with a high-intensity flashlamp. Sabrina M. Wenzel, MD et al. (Dermatology 2008; 217: 286 – 290)



A study which showed 90% clearance in telangiectasias without the risks associated with using Pulsed Dye Laser .

Clinical application of intense pulsed light in facial telangiectasis in 238 cases (Chinese J Aesth Plast Surg , Apr. 2008 , Vol. 19 , No. 2)

It is often said that clinical studies use only a few patients; here is a study on 238 Chinese patients that found all showed improvement of at least 30% from 1-3 treatments (over 40% showed at least 60% improvement). The study also reported an improvement in wrinkles following treatment.

Ellipse Nd:YAG treatments

Of course, it is possible to treat certain vessels with Ellipse Nd:YAG instead of Intense Pulsed Light.  Leg vessels respond much better to the longer wavelength of the Nd:YAG, but the Nd:YAG can also be used for difficult telangiectasias on the face.

Long-pulsed Nd:YAG laser: does it give clinical benefit of the treatment of facial telangiectasia? J. H. Lee et al. (Journal of the European Academy of Dermatology and venerology 2011)


Five men and seven women were enrolled (aged 43 ± 5.8 years). Total clearance of vessels was 78.3%. The number of vessels in diameter of 0.1 mm was reduced by 61.1% and that of vessels in diameter of 0.2–0.3 mm decreased by 92.2% on the average at 12-week follow-up. Eleven of 12 patients were very satisfied with the clinical results. One patient rated as ‘satisfied’ due to hyperpigmentation after the treatment, which improved at 2-week follow-up.

About ellipseblogger

Ellipseblogger is the collective name for the various service staff of Ellipse A/S; manufacturers of laser and Intense Pulsed Light (I2PL) solutions for aesthetic dermatology since 1997. Please note that this blog reflects our worldwide applications of Ellipse systems of which some may not be currently cleared for sale in the US.

Posted on September 6, 2013, in Medical, Treatments, Uncategorized and tagged , , , , , , , . Bookmark the permalink. Leave a comment.

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